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FACE RICH CREAM

4.7
4.7 out of 5
4.7 out of 5
(91)

Deep hydration clinically shown to firm, strengthen + replenish.

  • OS-01 Peptide™
  • Fine Lines
  • Wrinkles
  • Firmness
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
OS-01 FACE RICH CREAM Refill
Starter Kit 50 mL / 1.7 fl oz Refill 50 mL / 1.7 fl oz

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  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

Details
  • Our proprietary OS-01 Senescence-Blocking Peptide™ visibly slows cellular skin aging, resulting in skin that feels and acts younger over time
  • Dual-Phase Hydration System instantly draws in moisture and supports skin’s barrier for long-lasting hydration retention 
  • Clinically shown to help restore visible firmness, hydration, and smoothness in 12 weeks1
  • Rich, indulgent texture melts into skin without heaviness
Clinical proof
  • 100% saw improved hydration after 6 weeks1
  • 93% agreed their skin retains hydration better over time1
  • 97% saw a reduced appearance of fine lines and wrinkles after 6 weeks1
  • 93% saw improved visible firmness and elasticity after 6 weeks1
  • +38% increase in skin’s hydration after 12 weeks1

The Clinical Studies

Efficacy Study1

A 12-week, third-party, double-blind clinical study evaluated the effects of OS-01 FACE RICH CREAM in 29 female participants ages 43-65 with mild to moderate facial skin sagging, nasolabial folds, and expression lines. Participants applied OS-01 FACE RICH CREAM 2x daily to their face and neck. Barrier function and hydration were measured with instrumental devices (Corneometer, TEWL measurement), while radiance, texture,and hydration were evaluated visually and tactilely by expert clinical graders. Participants also provided subjective assessments via a self-reported questionnaire.

The results after 6 weeks:

  • 100% saw improved hydration
  • 93% agreed their skin retains hydration better over time
  • 97% saw a reduced appearance of fine lines and wrinkles
  • 93% saw improved visible firmness and elasticity
  • 97% reported smoother, softer, more radiant skin

The results after 12 weeks:

  • +38% increase in skin’s hydration
  • 97% had more hydrated skin
  • 97% reported improved overall appearance
  • 90% reported more nourished skin with improved skin quality
  • +37% improvement in skin smoothness
  • 83% agree their skin looks, feels, and acts more youthful
  • 81% saw reduced visible redness and irritation
  • +13% increase in barrier strength

Safety studies

OS-01 FACE RICH CREAM is non-comedogenic, dermatologist tested, suitable for sensitive skin, fragrance-free, and formulated without parabens, sulfates, phthalates, or other common irritants. Based on its formula and clinical testing, it has been awarded the National Eczema Association Seal of Acceptance™.

Our commitment to the scientific process

OneSkin products are validated with a rigorous process from the lab to the clinic: Lab testing on human skin to evaluate the effect on the cellular level, consumer testing with real users to ensure optimal texture and feel, and third-party clinical studies to evaluate the effect on the human level over time.
Ingredients

Formulated without
Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.

Ingredients
Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii (Shea) Nut Extract, Lauryl Olivate, Cetearyl Olivate, Euterpe Oleracea Fruit Oil, Squalane, C10-18 Triglycerides, Glyceryl Stearate SE, Linoleic/Oleic/Palmitic Triglyceride, Saccharide Isomerate, Sorbitan Olivate, Coconut Alkanes, 1,2-Hexanediol, Panthenol, Butyrospermum Parkii (Shea) Butter, Sodium PCA, Collagen Amino Acids, Ectoin, Citrullus Lanatus (Watermelon) Fruit Extract, Ceramide NP, Haematococcus Pluvialis Extract, Lens Esculenta (Lentil) Fruit Extract, Betaine, Coco-Caprylate/Caprate, Pyrus Malus (Apple) Fruit Extract, Moringa Oleifera Seed Oil, Decapeptide-52,* Hexapeptide-9, Tamarindus Indica Seed Polysaccharide, Limnanthes Alba (Meadowfoam) Seed Oil, Macadamia Integrifolia Seed Oil, Phytosphingosine, Sodium Lactate, Tremella Fuciformis Sporocarp Extract, Citric Acid, Sodium Citrate, Caprylyl Glycol, Phaeodactylum Tricornutum Extract, Cholesterol, Lecithin, Caprylhydroxamic Acid, Tocopherol, Propanediol, Sorbitan Oleate, Sorbitan Palmitate, Cetyl Palmitate, Dilinoleic Acid/Propanediol Copolymer, Sodium Phytate, Xanthan Gum, Cetearyl Alcohol, Hydroxyacetophenone, Sodium Benzoate. 
*OS-01 Peptide™

How to use

Smooth a generous layer onto clean, dry skin on the face, neck, and chest. Use 2x daily, morning and evening. Results require consistency. 

Complete the Protocol

As skin ages, it loses the density and barrier integrity that keep it resilient.

OS-01 FACE RICH CREAM instantly replenishes moisture while supporting skin’s barrier and structural density, leaving skin firmer-looking and better able to hold onto hydration.

An educational diagram of human skin layers, showing a healthy, resilient skin structure with labels pointing to the strong barrier, intact collagen, intact elastin, and abundant hyaluronic acid.
An explanatory cross-section diagram of skin layers with callouts reading 'Weak, depleted skin,' 'Weekended Barrier,' 'Fragmented Collagen,' 'Intact Elastin,' and 'Reduced Hyaluronic Acid.'
  • COLLAGEN

    The scaffolding that gives skin its strength and structure

  • ELASTIN

    Gives skin its elasticity and ability to snap back

  • HYALURONIC ACID

    Binds water molecules to keep skin hydrated and plump

OS-01 Peptide logo featuring a solid orange square on the left, followed by the text 'OS-01' in black and 'PEPTIDE' in bold black letters, with a small trademark symbol.

Engineered to reverse skin’s visible biological age.2

Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid, and barrier strength. The result: skin that looks, feels, and acts younger over time.

Explore the science →

Clinically validated results that build over time

93%

saw improved visible firmness and elasticity after 12 weeks1

+37%

improvement in skin smoothness after 12 weeks1

WEEK 1

Deep, replenishing hydration

  • The OS-01 Peptide™ gets to work immediately
  • Bioactive humectants draw hydration deep into skin
  • Skin-identical lipids seal the moisture barrier
WEEK 6

Firmer, more resilient skin

  • 100% saw improved hydration1
  • 93% agreed their skin retains hydration better over time1
  • 97% saw a reduced appearance of fine lines and wrinkles1
  • 93% saw improved visible firmness1
WEEK 12

Smoother, more youthful skin

  • +38% increase in skin’s hydration1
  • +37% smoother skin1
  • 97% reported improved overall appearance1
  • 90% reported more nourished skin with improved skin quality1
  • 83% agree their skin looks, feels, and acts more youthful1

Key ingredients

OS-01 Peptide™

Proven to reverse skin's visible biological age by reversing the visible effects of senescent (dysfunctional, aging) cells.

Palmless™ torula oil

A nourishing emollient power-packed with antioxidants that boosts barrier strength + reduces the appearance of fine lines and wrinkles.

Tremella fuciformis mushroom extract

A naturally derived extract that helps skin hold more hydration while supporting antioxidant defense.

Vegan collagen amino acids

Spermidine-rich upcycled microalgae shown to visibly boost collagen synthesis and volumize skin’s matrix.

Triple Lipid Barrier Complex (ceramide + cholesterol + free fatty acids)

A skin-identical blend of essential lipids that helps strengthen skin’s barrier.

All ingredients

Formulated without
Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.

Ingredients
Water (Aqua), Glycerin, Caprylic/Capric Triglyceride, Butyrospermum Parkii (Shea) Nut Extract, Lauryl Olivate, Cetearyl Olivate, Euterpe Oleracea Fruit Oil, Squalane, C10-18 Triglycerides, Glyceryl Stearate SE, Linoleic/Oleic/Palmitic Triglyceride, Saccharide Isomerate, Sorbitan Olivate, Coconut Alkanes, 1,2-Hexanediol, Panthenol, Butyrospermum Parkii (Shea) Butter, Sodium PCA, Collagen Amino Acids, Ectoin, Citrullus Lanatus (Watermelon) Fruit Extract, Ceramide NP, Haematococcus Pluvialis Extract, Lens Esculenta (Lentil) Fruit Extract, Betaine, Coco-Caprylate/Caprate, Pyrus Malus (Apple) Fruit Extract, Moringa Oleifera Seed Oil, Decapeptide-52,* Hexapeptide-9, Tamarindus Indica Seed Polysaccharide, Limnanthes Alba (Meadowfoam) Seed Oil, Macadamia Integrifolia Seed Oil, Phytosphingosine, Sodium Lactate, Tremella Fuciformis Sporocarp Extract, Citric Acid, Sodium Citrate, Caprylyl Glycol, Phaeodactylum Tricornutum Extract, Cholesterol, Lecithin, Caprylhydroxamic Acid, Tocopherol, Propanediol, Sorbitan Oleate, Sorbitan Palmitate, Cetyl Palmitate, Dilinoleic Acid/Propanediol Copolymer, Sodium Phytate, Xanthan Gum, Cetearyl Alcohol, Hydroxyacetophenone, Sodium Benzoate. 
*OS-01 Peptide™

OneSkin Longevity Protocol

OS-01 FACE RICH CREAM Refill

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91 reviews
  • JM
    Janet M.
    Verified Buyer
    Reviewing
    OS-01 FACE RICH CREAM
    I recommend this product
    Rated 5 out of 5 stars
    3 minutes ago
    Incredible!

    I have seen a huge improvement in my skin. My skin feels plumper and more moisturized. It is not heavy and doesn’t feel heavy or oily. It is hands down the best!!

    Was this helpful?
  • BP
    Barbara P.
    Verified Buyer
    Reviewing
    OS-01 FACE RICH CREAM
    I recommend this product
    Rated 5 out of 5 stars
    51 minutes ago
    Love this new cream!

    This is rich but not oily or greasy, my skin looks and feels so nice and I like the way the product is disbursed from the center at the top! I use this now instead of the face moisturizer and it is way better!

    Was this helpful?
  • VT
    victoria t.
    Verified Buyer
    Reviewing
    OS-01 FACE RICH CREAM
    I recommend this product
    Rated 5 out of 5 stars
    3 hours ago
    Fantastic

    This face cream is rich but not heavy. Perfect for my dry and older skin. So glad you developed this product.

    Was this helpful?
  • MP
    Michele P.
    Verified Buyer
    Reviewing
    OS-01 FACE RICH CREAM
    I recommend this product
    Rated 5 out of 5 stars
    4 hours ago
    AGE GRACEFULLY

    This now RICH FACE CREAM is what we need as we get up in age. No more creepy stuff and dry desert vibes. Thank you One Skin.

    Was this helpful?
  • FT
    Fernanda T.
    Verified Buyer
    Reviewing
    OS-01 FACE RICH CREAM
    I recommend this product
    Rated 5 out of 5 stars
    4 hours ago
    Muito bom

    Já utilizava o normal que adoro, mas ainda gosto mais deste por ser mais hidratante ainda, tal como o outro deixa a pela muito suave, muito hidratada durante todo o dia e pele muito bonita e saudável.

    Tenho 58 anos e pele muito seca.

    Was this helpful?
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Frequently Asked Questions

Which one is right for my skin type: OS-01 FACE RICH CREAM or OS-01 FACE MOISTURIZER?

OS-01 FACE MOISTURIZER provides lightweight hydration and is suitable for oily, combination, and normal skin. OS-01 FACE RICH CREAM delivers deep hydration in a rich, replenishing texture and is suitable for dry, depleted, or mature skin. As seasons and climates change, you may choose to switch between the two depending on your hydration needs.

How long does OS-01 FACE RICH CREAM last?

With twice-daily use, one 50ml jar should last approximately 1–2 months. This varies from person to person depending on how much you use per application, but many people find that 1–2 pumps generously cover the face and neck.

Can I wear OS-01 FACE RICH CREAM under makeup during the day, or is it strictly a night cream?

OS-01 FACE RICH CREAM can be used day and night, depending on your skin's needs. You can use OS-01 FACE MOISTURIZER as a lightweight daytime moisturizer and OS-01 FACE RICH CREAM as a night cream—or use OS-01 FACE RICH CREAM morning and evening if you have dry, depleted skin, are in a dry climate or season, or just want a little extra hydration.

 

OS-01 FACE RICH CREAM can work well under makeup, but we always recommend patch testing with your specific makeup to ensure the combination works well for you. We recommend giving it a few minutes to fully absorb before applying makeup on top.

Can I switch between OS-01 FACE RICH CREAM and OS-01 FACE MOISTURIZER depending on the season?

Yes. You may choose to use OS-01 FACE MOISTURIZER in warmer, more humid months and OS-01 FACE RICH CREAM when skin feels drier in winter. Because both contain optimal levels of the OS-01 Peptide™, you get skin longevity benefits either way.

IS OS-01 FACE RICH CREAM safe for sensitive skin?

OS-01 FACE RICH CREAM is suitable for sensitive skin, non-comedogenic, dermatologist tested, fragrance free, and formulated without parabens, sulfates, phthalates, or other common irritants. Based on its formula and clinical testing, it has been awarded the National Eczema Association Seal of Acceptance™. Additionally, it contains barrier-supporting and hydrating ingredients, including a Triple Lipid Barrier Complex (ceramides, cholesterol, and free fatty acids), ectoin, and tremella mushroom extract—ingredients generally recognized for their gentle and soothing properties. In consumer testing, 87% of users agreed the cream deeply moisturizes and comforts dry skin.1

 

That said, as with any new skincare product, we recommend patch testing before full application, especially for those with known sensitivities or reactive skin conditions.

Citations

  1. Based on a double-blind, third-party 12-week clinical study with 29 participants aged 43-65.
  2. Visible biological age defined as signs of aging such as smoothness and barrier strength. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)