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FULL-SIZE LIP + BODY GIFT SET

4.6
4.6 out of 5
4.6 out of 5
(3,391)

Hydrating + smoothing longevity routine for the lips and body.

  • Age-Reversal Peptide
  • Smoothing
  • Replenishing
  • Hydrating
FULL-SIZE LIP + BODY GIFT SET
Limited Edition
FULL-SIZE LIP + BODY GIFT SET
FULL-SIZE LIP + BODY GIFT SET
FULL-SIZE LIP + BODY GIFT SET
Before-and-after comparison of a person's inner arm showing skin texture improvement, labeled 'BODY MOISTURIZER' with 'BEFORE' and 'AFTER 12 WEEKS' text.
Before-and-after comparison of a lip mask product showing reduced fine lines and wrinkles on lips after 12 weeks. The top panel is labeled 'LIP MASK' and 'BEFORE,' while the bottom panel is labeled 'AFTER 12 WEEKS' with '87% saw reduced fine lines and wrinkles on lips.
FULL-SIZE LIP + BODY GIFT SET
FULL-SIZE LIP + BODY GIFT SET
Limited Edition
FULL-SIZE LIP + BODY GIFT SET
FULL-SIZE LIP + BODY GIFT SET
FULL-SIZE LIP + BODY GIFT SET
Before-and-after comparison of a person's inner arm showing skin texture improvement, labeled 'BODY MOISTURIZER' with 'BEFORE' and 'AFTER 12 WEEKS' text.
Before-and-after comparison of a lip mask product showing reduced fine lines and wrinkles on lips after 12 weeks. The top panel is labeled 'LIP MASK' and 'BEFORE,' while the bottom panel is labeled 'AFTER 12 WEEKS' with '87% saw reduced fine lines and wrinkles on lips.
FULL-SIZE LIP + BODY GIFT SET

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  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

  • Certified cruelty-free by The Leaping Bunny

  • Approved by the National
Eczema Association

  • Certified plastic neutral in partnership with RePurpose

Details
  • Hydrate, replenish, and fortify skin against seasonal dryness and time itself with a full-size duo for the lips and body, powered by our proprietary OS-01 Senescence-Blocking Peptide™
  • OS-01 BODY MOISTURIZER targets a root cause of crepiness while visibly firming for younger-looking, healthier body skin2
  • OS-01 LIP MASK helps restore what dry weather and aging take away—delivering overnight hydration and smoother, fuller-looking lips with consistent use1
  • Sleek, durable, and water-resistant, the travel bag is built to go wherever the season takes you—with a design as fit for your counter as it is your carry-on suitcase.
Clinical proof

OS-01 LIP MASK

  • 98% agreed their lips stayed moisturized overnight1
  • 81% saw reduced appearance of wrinkles around the lips after 4 weeks1
  • 81% reported visibly fuller lips after 8 weeks1

OS-01 BODY MOISTURIZER

  • +41% increase in skin’s barrier resilience after 12 weeks2
  • +38% increase in hydration after 12 weeks2
  • 70% reported visibly smoother texture and improved general appearance2

The Clinical Studies

OS-01 LIP MASK: 12-Week Consumer Perception Study1

A 12-week consumer perception study evaluated the effects of OS-01 LIP MASK on hydration, smoothness, visible fullness, and the appearance of fine lines around and on the lips with nightly application.

Immediate results:

  • 98% agreed lips feel instantly hydrated upon application
  • 98% agreed lips feel hydrated and moisturized 8+ hours after application
  • 95% agreed it applies smoothly and is ultra-hydrating

4 weeks:

  • 95% agreed lips feel smoother
  • 81% reported reduced appearance of fine lines around the lip border
  • 80% reported reduced appearance of fine lines on the lips
  • 78% reported improved visible lip fullness

12 weeks:

  • 97% agreed lips feel smoother
  • 94% agreed lips retain hydration longer
  • 87% reported reduced appearance of fine lines and wrinkles on the lips
  • 81% agreed lips feel more resilient
  • 72% agreed the natural color of their lips improved


OS-01 BODY MOISTURIZER: 3-Month Efficacy Study2

A 12-week, double-blind, third-party clinical study evaluated the effects of OS-01 BODY MOISTURIZER on body skin hydration, barrier function, texture, and appearance. 60 participants were divided into two groups: one applied OS-01 BODY twice daily, while the other applied a placebo moisturizer twice daily. Hydration and trans-epidermal water loss (TEWL) were measured with instrumental devices (Corneometer and Tewameter). Participants also reported subjective improvements. Published in the Journal of Cosmetic Dermatology, Zonari et al., 2025.

The results after 12 weeks:

  • 93% of participants reported improved skin hydration
  • +38% improvement in forearm and upper arm hydration (corneometer)
  • +41% improvement in skin barrier on forearm and +35% on upper arm (tewameter)
  • 70% reported improved skin texture
  • 70% reported improved overall appearance

Safety studies

OS-01 BODY MOISTURIZER and OS-01 LIP MASK are non-comedogenic, dermatologist tested, suitable for sensitive skin, fragrance-free, and formulated without parabens, sulfates, phthalates, or other common irritants. Based on their formulas and clinical testing, they have been awarded the National Eczema Association Seal of Acceptance™.

Our commitment to the scientific process

OneSkin products are validated with a rigorous process from the lab to the clinic: Lab testing on human skin to evaluate the effect on the cellular level, consumer testing with real users to ensure optimal texture and feel, and third-party clinical studies to evaluate the effect on the human level over time.
Ingredients

Formulated without
Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.

OS-01 LIP MASK ingredients:
Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan.
*OS-01 Peptide™

OS-01 BODY MOISTURIZER ingredients:
Water (Aqua), Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Squalane, Avena Sativa (Oat) Kernel Oil, Prunus Domestica Seed Oil, Cetearyl Olivate, Mangifera Indica (Mango) Seed Butter, Saccharide Isomerate, Panthenol, Tremella Fuciformis Sporocarp Extract, Tocopheryl Acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NG, Galactoarabinan, Lepidium Sativum Sprout Extract, Soy Isoflavones, Niacinamide, Betaine, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol.
*OS-01 Peptide™

This set includes

White bottle with black pump and 'One Skin' logo on a beige background

STEP 1

OS-01 BODY MOISTURIZER

Nourishing hydration designed to strengthen crepey skin.

Size

250 mL / 8.45 fl oz

How to use

Apply to arms, legs, chest, back, and stomach and massage until absorbed. Use 2x daily.

An open black One Skin cushion foundation compact, showing the warm beige foundation powder and the built-in mirror inside the lid, set against a clean off-white background.

STEP 2

OS-01 LIP MASK

Overnight lip care for visibly smoother, fuller lips over time.

Size

7 mL / 0.24 fl oz

How to use

Using the metal applicator, apply a generous layer onto clean, dry lips as needed. For a deep treatment, apply before bed and leave on overnight.

A metallic silver cosmetic pouch with a black zipper, featuring the debossed brand name 'ONE SKIN' in the center and an orange drawstring tag on the left side, set against a plain light gray background.

Signature Travel Bag

A dopp kit for your longevity skincare and travel necessities.

Size

0.8 gal / 5.1"H x 4.3"D x 8.3"W

How to clean

Hand wash and spot clean with a cool, damp cloth only—do not bleach, iron, tumble dry, or dry clean.

OS-01 Peptide logo featuring a solid orange square on the left, followed by the text 'OS-01' in black and 'PEPTIDE' in bold black letters, with a small trademark symbol.

Engineered to reverse skin’s visible biological age.3

Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid and barrier strength. The result: skin that looks, feels, and acts younger over time.

Explore the science →
Close-up before-and-after comparison of a person's lips, showing a matte pink lip color applied in the after photo after 4 weeks. The top panel is labeled BEFORE and shows natural, uncolored lips, while the bottom panel is labeled AFTER 4 WEEKS and shows the colored, hydrated lips.

78%

reported improved visible fullness after 4 weeks1

Close-up before-and-after comparison of a person's lips, with the top labeled BEFORE and the bottom labeled AFTER 12 WEEKS. The lower lip appears more hydrated and glossy in the after view.

97%

agreed lips feel and look smoother after 12 weeks1

Close-up before-and-after comparison of lips, with the top panel labeled BEFORE and the bottom panel labeled AFTER 12 WEEKS. The image shows skin texture and lip condition over time.

81%

saw reduced appearance of wrinkles around the lips after 4 weeks1

Clinically validated results that build over time.

Week 1

Instant hydration you can feel 

  • Melts into a non-sticky overnight layer
  • 98% agreed lips feel instantly hydrated on application1
  • The OS-01 Peptide™ begins working on contact
Week 4

Smoother lips, fewer fine lines

  • 95% agreed lips feel smoother1
  • 81% saw reduced appearance of fine lines around the lip border1
  • 80% saw reduced appearance of fine lines on the lips1
Week 12

Resilient, fuller, healthier lips

  • 97% agreed lips feel smoother1
  • 87% reported reduced appearance of fine lines and wrinkles on the lips1
  • 94% agreed lips retain hydration for longer1

Key Ingredients

A single irregular, smooth, off-white to light gray solid piece with a glossy surface, centered on a solid black background.
OS-01 Peptide™

Proven to reverse skin's visible biological age by reversing the visible effects of senescent (dysfunctional, aging) cells.

Tremella mushroom extract

A naturally derived extract that helps skin hold more hydration while supporting antioxidant defense.

Ceramides

Support skin’s natural lipid barrier to protect, boost moisture retention, and visibly repair dry and sensitive skin.

Sulforaphane

A powerful plant-derived antioxidant known to protect skin against the visible effects of environmental stressors and oxidative damage.

Saccharide isomerate

A plant-derived moisture magnet that binds to skin for up to 72 hours of hydration support.

All Ingredients

Formulated without
Our products are formulated without fragrance, parabens, sulfates, lanolin, MCI/MI, DEA, heavy metals, talc, petrolatum/paraffin/mineral oil, gluten, phthalates, and PFAs. We also avoid unnecessary emulsifiers, preservatives, and solvents.


OS-01 BODY MOISTURIZER ingredients:
Water (Aqua), Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Squalane, Avena Sativa (Oat) Kernel Oil, Prunus Domestica Seed Oil, Cetearyl Olivate, Mangifera Indica (Mango) Seed Butter, Saccharide Isomerate, Panthenol, Tremella Fuciformis Sporocarp Extract, Tocopheryl Acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NG, Galactoarabinan, Lepidium Sativum Sprout Extract, Soy Isoflavones, Niacinamide, Betaine, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol.
*OS-01 Peptide™


OS-01 LIP MASK ingredients:
Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan.
*OS-01 Peptide™

OneSkin Longevity Protocol

FULL-SIZE LIP + BODY GIFT SET

Write a Review (Opens in a new tab)
3,391 reviews
  • S
    Susan
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    5 minutes ago
    5 Stars

    Love it

    Was this helpful?
  • JM
    Joanna M.
    Verified Reviewer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    2 hours ago
    BODY MOISTURIZER

    Enjoying this moisturizer! Goes on so smooth and no greasy residue. I’m glad it has ingredients that help with creepiness as I am 61. Only been using for a few months but seeing improvement.

    Was this helpful?
  • BW
    Bettina W.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    3 hours ago
    Favorite!

    This is my only nighttime lip product. Apply right before bed & wake up with smooth, plumped lips

    Was this helpful?
  • JW
    Jennifer W.
    Verified Buyer
    Reviewing
    OS-01 LIP Mask, Recurring
    I recommend this product
    Rated 5 out of 5 stars
    18 hours ago
    This product works

    I had incurably chapped lips. I couldn’t keep enough Vaseline on them. I got lip Product to resolve this problem.

    I knew there was a claim that it could also make lips plumper, but I wasn’t getting my hopes up on that

    But after a few months of use, I noticed my lips were pumper and better shaped

    And very happy with this product and I’ll continue to use it as it has brought me wonderful results that no other lip product has been able to deliver on

    Was this helpful?
  • D
    Dashia
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    5 Stars

    Smells great! Absorbs wonderfully!

    Was this helpful?
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Citations

  1. Based on a 12-week consumer perception study with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK.
  2. Based on a double-blind, third-party 12-week clinical study with 27 participants aged 62–82. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2025.)
  3. Visible biological age defined as signs of aging such as smoothness and barrier strength. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)